⚡ Quick Summary
A recent study demonstrated that a personalized nutrition intervention using concentrated high-protein, high-calorie oral nutritional supplements (cHPHC-ONS) significantly improved clinical outcomes in patients with disease-related malnutrition (DRM). The intervention led to notable reductions in malnutrition prevalence and enhancements in muscle mass and function over three months.
🔍 Key Details
- 📊 Participants: 65 patients with disease-related malnutrition
- 🍽️ Intervention: Concentrated high-protein, high-calorie oral nutritional supplements (cHPHC-ONS)
- 🧪 Assessment Tools: AI-assisted morphofunctional assessment and muscle ultrasonography
- ⏳ Duration: Baseline (B0) and three months (M3) post-intervention
🔑 Key Takeaways
- 📉 Weight Loss: Significant decrease in percentage weight loss from B0 (-6.75 ± 7.5%) to M3 (0.5 ± 3.48%) (p < 0.01).
- 📉 Malnutrition Rates: Prevalence of malnutrition decreased from 93.4% at B0 to 78.9% at M3 (p < 0.01).
- 📉 Severe Malnutrition: Reduced from 60.7% at B0 to 40.3% at M3 (p < 0.01).
- 📉 Sarcopenia: Prevalence decreased from 19.4% at B0 to 15.5% at M3 (p < 0.04).
- 💪 Muscle Area: Increased significantly (p = 0.03).
- 📈 Muscle Function: Improvements in muscle thickness (p = 0.04), pennation angle (p = 0.02), and handgrip strength (p = 0.04) in patients aged ≥60.
📚 Background
Malnutrition, particularly in patients with chronic diseases, poses a significant challenge to healthcare providers. Effective assessment and intervention strategies are essential for improving patient outcomes. This study aimed to evaluate the effectiveness of a novel oral nutritional supplement combined with advanced AI-assisted assessments to monitor and enhance the nutritional status of malnourished patients.
🗒️ Study
Conducted as a prospective observational study, this research involved 65 patients diagnosed with disease-related malnutrition. Participants received concentrated high-protein, high-calorie oral nutritional supplements (cHPHC-ONS) as part of their usual clinical care. Comprehensive assessments were performed at baseline and three months after the intervention to evaluate changes in nutritional status and muscle function.
📈 Results
The findings revealed a significant reduction in weight loss and malnutrition prevalence among participants. Specifically, the percentage weight loss decreased significantly, and the prevalence of both malnutrition and severe malnutrition showed marked improvement. Additionally, muscle area and function improved, particularly in older patients, highlighting the effectiveness of the cHPHC-ONS intervention.
🌍 Impact and Implications
This study underscores the potential of personalized nutrition interventions in managing disease-related malnutrition. By integrating AI-assisted assessments with targeted nutritional support, healthcare providers can significantly enhance patient outcomes, reduce malnutrition rates, and improve muscle mass and function. Such approaches could transform care strategies for malnourished patients, leading to better health and quality of life.
🔮 Conclusion
The results of this study highlight the effectiveness of concentrated high-protein, high-calorie oral nutritional supplements in addressing malnutrition in patients with chronic diseases. By employing personalized interventions and advanced assessment techniques, healthcare professionals can make substantial strides in improving the nutritional status and overall health of vulnerable populations. Continued research in this area is essential to further validate these findings and explore broader applications.
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Effectiveness of High-Protein Energy-Dense Oral Supplements on Patients with Malnutrition Using Morphofunctional Assessment with AI-Assisted Muscle Ultrasonography: A Real-World One-Arm Study.
Abstract
Background: User-friendly tools for assessing nutrition status and interventions in malnourished patients are crucial. This study evaluated the effectiveness of a personalised nutrition intervention using a novel oral nutritional supplement and AI-supported morphofunctional assessment to monitor clinical outcomes in patients with disease-related malnutrition (DRM). Methods: This prospective observational study involved patients receiving concentrated high-protein, high-calorie ONS (cHPHC-ONS), per usual clinical practice. Comprehensive assessments were performed at baseline (B0) and three months (M3) post-intervention. Results: 65 patients participated in the study. Significant decreases were observed in the percentage weight loss from B0 (-6.75 ± 7.5%) to M3 (0.5 ± 3.48%) (p < 0.01), in the prevalence of malnutrition (B0: 93.4%; M3: 78.9%; p < 0.01), severe malnutrition (B0: 60.7%; M3: 40.3%; p < 0.01), and sarcopenia (B0: 19.4%; M3: 15.5%; p < 0.04). Muscle area increased (p = 0.03), and there were changes in the echogenicity of the rectus femoris muscle (p = 0.03) from B0 to M3. In patients aged ≥60, an increase in muscle thickness (p = 0.04), pennation angle (p = 0.02), and handgrip strength (p = 0.04) was observed. There was a significant reduction in the prevalence of malnutrition (B0: 93.4%; M3: 78.9%; p < 0.01) and severe malnutrition (B0: 60.7%; M3: 40.3%; p < 0.01). Conclusions: In patients with DRM, a personalised intervention with cHPHC-ONS significantly reduces the prevalence of malnutrition, severe malnutrition, and sarcopenia and improves muscle mass and function.
Author: [‘López-Gómez JJ’, ‘Primo-Martín D’, ‘Cebria A’, ‘Izaola-Jauregui O’, ‘Godoy EJ’, ‘Pérez-López P’, ‘Jiménez Sahagún R’, ‘Ramos Bachiller B’, ‘González Gutiérrez J’, ‘De Luis Román DA’]
Journal: Nutrients
Citation: López-Gómez JJ, et al. Effectiveness of High-Protein Energy-Dense Oral Supplements on Patients with Malnutrition Using Morphofunctional Assessment with AI-Assisted Muscle Ultrasonography: A Real-World One-Arm Study. Effectiveness of High-Protein Energy-Dense Oral Supplements on Patients with Malnutrition Using Morphofunctional Assessment with AI-Assisted Muscle Ultrasonography: A Real-World One-Arm Study. 2024; 16:(unknown pages). doi: 10.3390/nu16183136