ā” Quick Summary
A recent study in Italy highlights that raising awareness about hematopoietic stem cell donation can significantly increase the likelihood of individuals registering as donors. Utilizing artificial intelligence, the research found that higher knowledge levels correlate with a greater willingness to donate.
š Key Details
- š Participants: 1,518 respondents
- š§© Groups: Donor group (registered) vs. Non-donor group (not registered)
- āļø Methodology: Online survey shared via social media
- š Machine Learning: Six classifiers trained to predict IBMDR registration probability
- š Performance: AUC ranging from 0.65 to 0.81
š Key Takeaways
- š Knowledge is key: 51.7% of donors had a higher knowledge level compared to 24.4% of non-donors.
- š Negative feelings: Non-donors reported fear, confusion, and uncertainty regarding donation.
- š” Awareness campaigns: Essential for improving donor registration rates.
- š¤ AI’s role: Machine learning can effectively predict donor registration likelihood.
- š National implications: Findings are crucial for addressing donor shortages in Italy.
š Background
In Italy, the demand for hematopoietic stem cell transplants often surpasses the available compatible donors in the Italian Bone Marrow Donor Registry (IBMDR). Understanding the public’s knowledge, beliefs, and feelings about stem cell donation is vital for addressing this gap and enhancing donor recruitment strategies.
šļø Study
The study utilized an online survey distributed through social media platforms to gather insights from the Italian population. Participants were categorized into two groups: those who were registered as donors and those who had never registered. The survey aimed to assess their knowledge and feelings about stem cell donation, providing a comprehensive view of the factors influencing donor registration.
š Results
The analysis revealed that individuals in the non-donor group exhibited a significantly lower level of knowledge about the need for stem cell donations. Additionally, negative emotions such as fear, confusion, and uncertainty were prevalent among non-donors. The study confirmed that increased knowledge was associated with a higher likelihood of registering as a donor, with machine learning classifiers achieving an AUC between 0.65 and 0.81, indicating a moderate to good predictive capability.
š Impact and Implications
The findings of this study underscore the critical need for enhanced awareness and educational initiatives regarding hematopoietic stem cell donation. By addressing knowledge gaps and alleviating fears, healthcare organizations can significantly improve donor registration rates, ultimately saving lives through increased availability of compatible donors for transplants.
š® Conclusion
This research highlights the importance of awareness in increasing hematopoietic stem cell donations. By leveraging artificial intelligence and focusing on educational outreach, we can foster a more informed public that is willing to contribute to this life-saving cause. The future of stem cell donation in Italy could be transformed through strategic awareness campaigns and improved public understanding.
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Raising awareness may increase the likelihood of hematopoietic stem cell donation: a nationwide survey using artificial intelligence.
Abstract
BACKGROUND: In Italy, the demand for allogeneic transplantation exceeds the number of compatible donors in the Italian Bone Marrow Donor Registry (IBMDR). This study aimed to explore the knowledge, beliefs, opinions, values, and feelings of the Italian population regarding stem cell donation.
METHODS: An online survey was shared via social media. Respondents were retrospectively identified as registered on the IBMDR (donor group) or never registered (non-donor group). Statistical analyses confirmed the relationship between knowledge level and willingness to donate. Six machine learning classifiers were trained using questionnaire responses to predict the probability of IBMDR registration.
RESULTS: A total of 1518 respondents participated. Characteristics identified in the non-donor group were a lower level of knowledge regarding donation needs (51.7% vs 24.4%, pā<ā0.001) and negative feelings such as fear (Zā=ā-Ā 2.2642, pā=ā0.02), confusion (Zā=ā4.4821, pā<ā0.001), and uncertainty (Zā=ā3.3425, pā<ā0.001). Higher knowledge predicted a greater likelihood of IBMDR enrollment. Machine learning analysis showed an AUC ranging from 0.65 to 0.81, depending on the classifier.
CONCLUSIONS: The results underscore the need to improve strategies to raise awareness and knowledge of stem cell donation among the Italian population.
Author: [‘Conte L’, ‘De Nunzio G’, ‘Lupo R’, ‘Cascio D’, ‘Cioce M’, ‘Vitale E’, ‘Ianne C’, ‘Rubbi I’, ‘Martino M’, ‘Lombardini L’, ‘Vassanelli A’, ‘Pupella S’, ‘Pollichieni S’, ‘Sacchi N’, ‘Ciceri F’, ‘Botti S’]
Journal: Int J Hematol
Citation: Conte L, et al. Raising awareness may increase the likelihood of hematopoietic stem cell donation: a nationwide survey using artificial intelligence. Raising awareness may increase the likelihood of hematopoietic stem cell donation: a nationwide survey using artificial intelligence. 2024; (unknown volume):(unknown pages). doi: 10.1007/s12185-024-03894-x