โก Quick Summary
This study investigates the optimization of adult-oriented artificial intelligence (AI) for analyzing pediatric chest radiographs, revealing that the optimal operating points differ significantly for various lung lesions. By adjusting these points, the study demonstrates improved diagnostic performance, particularly for younger patients.
๐ Key Details
- ๐ Dataset: 4,727 chest radiographs from children under 19 years
- ๐งฉ Features used: Lung lesions including pneumothorax, consolidation, nodules, and pleural effusion
- โ๏ธ Technology: Commercial adult-oriented AI software
- ๐ Performance: Optimal operating points: 11% for pneumothorax, 14% for consolidation, 15% for nodules, 6% for pleural effusion
๐ Key Takeaways
- ๐ AI optimization is crucial for accurate pediatric chest radiograph analysis.
- ๐ Adjusting operating points can enhance sensitivity and specificity for different lesion types.
- ๐ถ Younger patients (especially under 2 years) benefit from a lower operating point for pneumothorax detection.
- ๐ Study period: March to November 2021.
- ๐ ROC curve analysis was employed to determine optimal thresholds.
- ๐ฅ Collaboration with pediatric radiologists ensured accurate ground truth for lesion presence.
- ๐ Findings could lead to better diagnostic tools in pediatric radiology.
๐ Background
The use of artificial intelligence in medical imaging has gained traction, particularly in adult populations. However, pediatric patients present unique challenges due to anatomical and physiological differences. This study aims to bridge the gap by optimizing AI tools originally designed for adults, ensuring they are effective for children as well.
๐๏ธ Study
Conducted by a team of researchers, this study analyzed chest radiographs from patients under 19 years old, collected over several months in 2021. The goal was to assess whether the AI’s performance could be improved by adjusting its operating points based on the specific needs of pediatric patients.
๐ Results
The analysis revealed that the optimal operating points for detecting various lung lesions in children were significantly different from the standard adult settings. Specifically, the optimal points were found to be 11% for pneumothorax, 14% for consolidation, 15% for nodules, and 6% for pleural effusion. Notably, a 3% operating point was particularly effective for improving sensitivity in detecting pneumothorax in children under 2 years old.
๐ Impact and Implications
The findings from this study have the potential to significantly enhance the diagnostic capabilities of AI in pediatric radiology. By tailoring AI tools to the specific characteristics of pediatric patients, healthcare providers can achieve more accurate diagnoses, leading to better patient outcomes. This research paves the way for future advancements in AI applications across various medical fields.
๐ฎ Conclusion
This study highlights the importance of optimizing artificial intelligence for pediatric applications, demonstrating that adjustments to operating points can lead to improved diagnostic performance. As we continue to integrate AI into healthcare, it is essential to consider the unique needs of different patient populations, ensuring that technology serves to enhance care for all.
๐ฌ Your comments
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Optimizing adult-oriented artificial intelligence for pediatric chest radiographs by adjusting operating points.
Abstract
The purpose of this study was to evaluate whether the optimal operating points of adult-oriented artificial intelligence (AI) software differ for pediatric chest radiographs and to assess its diagnostic performance. Chest radiographs from patients under 19 years old, collected between March and November 2021, were divided into test and exploring sets. A commercial adult-oriented AI software was utilized to detect lung lesions, including pneumothorax, consolidation, nodule, and pleural effusion, using a standard operating point of 15%. A pediatric radiologist reviewed the radiographs to establish ground truth for lesion presence. To determine the optimal operating points, receiver operating characteristic (ROC) curve analysis was conducted, varying thresholds to balance sensitivity and specificity by lesion type, age group, and imaging method. The test set (4,727 chest radiographs, mean 7.2โยฑโ6.1 years) and exploring set (2,630 radiographs, mean 5.9โยฑโ6.0 years) yielded optimal operating points of 11% for pneumothorax, 14% for consolidation, 15% for nodules, and 6% for pleural effusion. Using a 3% operating point improved pneumothorax sensitivity for children under 2 years, portable radiographs, and anteroposterior projections. Therefore, optimizing operating points of AI based on lesion type, age, and imaging method could improve diagnostic performance for pediatric chest radiographs, building on adult-oriented AI as a foundation.
Author: [‘Shin HJ’, ‘Han K’, ‘Son NH’, ‘Kim EK’, ‘Kim MJ’, ‘Gatidis S’, ‘Vasanawala S’]
Journal: Sci Rep
Citation: Shin HJ, et al. Optimizing adult-oriented artificial intelligence for pediatric chest radiographs by adjusting operating points. Optimizing adult-oriented artificial intelligence for pediatric chest radiographs by adjusting operating points. 2024; 14:31329. doi: 10.1038/s41598-024-82775-z