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🧑🏼‍💻 Research - October 14, 2024

Obsessive-compulsive symptoms relating to psychosocial functioning for people with schizophrenia, schizoaffective disorder, or bipolar disorder.

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⚡ Quick Summary

This study examined the impact of obsessive-compulsive symptoms (OCS) and obsessive-compulsive disorder (OCD) on the psychosocial functioning of individuals diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder. The findings revealed that comorbid OCS/OCD significantly correlates with poorer outcomes in relationships, activities of daily living, and living conditions.

🔍 Key Details

  • 📊 Dataset: 15,412 subjects diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder
  • 🧩 Timeframe: January 2007 to December 2016
  • ⚙️ Technology: Natural Language Processing (NLP) algorithms for data extraction
  • 🏆 Key Metrics: 15.3% experienced OCS without OCD; 16.8% had OCD

🔑 Key Takeaways

  • 📊 Comorbid OCS/OCD is prevalent among individuals with severe mental health disorders.
  • 💡 Presence of OCS/OCD is linked to significant challenges in psychosocial functioning.
  • 👩‍🔬 Relationships are notably affected, with an adjusted odds ratio of 1.34.
  • 🏆 Activities of Daily Living (ADLs) also show increased difficulties (adj.OR = 1.31).
  • 🌍 Living conditions are similarly impacted, indicating a need for comprehensive care.
  • 🆔 Study conducted at South London and Maudsley NHS Foundation Trust.
  • 📈 Importance of early identification and treatment of comorbid OCS in vulnerable populations.

📚 Background

Individuals with schizophrenia, schizoaffective disorder, and bipolar disorder often face a myriad of challenges that affect their daily lives. Among these challenges, obsessive-compulsive symptoms can exacerbate existing difficulties, leading to a decline in overall psychosocial functioning. Understanding the interplay between these symptoms and mental health disorders is crucial for developing effective treatment strategies.

🗒️ Study

The research utilized data from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre, employing the Clinical Record Interactive Search (CRIS) system to analyze electronic health records. The study aimed to assess the relationship between OCS/OCD and various aspects of psychosocial functioning, including activities of daily living, living conditions, and interpersonal relationships.

📈 Results

Out of the 15,412 subjects analyzed, 2,358 (15.3%) experienced OCS without OCD, while 2,586 (16.8%) had a recorded diagnosis of OCD. The presence of OCS/OCD was significantly associated with increased problems in relationships (adj.OR = 1.34), activities of daily living (adj.OR = 1.31), and living conditions (adj.OR = 1.31). These results underscore the detrimental impact of comorbid symptoms on psychosocial well-being.

🌍 Impact and Implications

The findings of this study highlight the critical need for healthcare providers to recognize and address comorbid obsessive-compulsive symptoms in patients with severe mental health disorders. By improving identification and treatment strategies, we can enhance the psychosocial functioning and overall quality of life for these vulnerable individuals. This research paves the way for future studies aimed at developing targeted interventions.

🔮 Conclusion

This study emphasizes the significant relationship between obsessive-compulsive symptoms and psychosocial functioning in individuals with severe mental health disorders. The evidence suggests that addressing these comorbid symptoms is essential for improving patient outcomes. Continued research in this area is vital for developing effective treatment protocols that can lead to better psychosocial support for affected individuals.

💬 Your comments

What are your thoughts on the impact of obsessive-compulsive symptoms in individuals with severe mental health disorders? We invite you to share your insights and engage in a discussion! 💬 Leave your comments below or connect with us on social media:

Obsessive-compulsive symptoms relating to psychosocial functioning for people with schizophrenia, schizoaffective disorder, or bipolar disorder.

Abstract

To assess the psychosocial functioning concerning obsessive-compulsive symptoms (OCS) and/or obsessive-compulsive disorder (OCD) comorbidity in people with schizophrenia, schizoaffective disorder, or bipolar disorder diagnosed in a large case register database in Southeast London. Data were retrieved from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) register using Clinical Record Interactive Search (CRIS) system, a platform allowing research on full but de-identified electronic health records for secondary and tertiary mental healthcare services. Information of schizophrenia, schizoaffective disorder, bipolar disorder diagnosis and OCS/OCD status was ascertained from structural or free-text fields through natural language processing (NLP) algorithms based on artificial intelligence techniques during the observation window of January 2007 to December 2016. Associations between comorbid OCS/OCD and recorded Health of the Nation Outcome Scales (HoNOS) for problems with activities of daily living (ADLs), living conditions, occupational and recreational activities, and relationships were estimated by logistic regression with socio-demographic confounders controlled. Of 15,412 subjects diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder, 2,358 (15.3%) experienced OCS without OCD, and 2,586 (16.8%) had OCD recorded. The presence of OCS/OCD was associated with more problems with relationships (adj.OR = 1.34, 95% CI: 1.25-1.44), ADLs (adj.OR = 1.31, 95%CI: 1.22-1.41), and living conditions (adj.OR = 1.31, 95% CI: 1.22-1.41). Sensitivity analysis revealed similar outcomes. Comorbid OCS/OCD was associated with poorer psychosocial functioning in people with schizophrenia, schizoaffective disorder, or bipolar disorder. This finding highlights the importance of identification and treatment of comorbid OCS among this vulnerable patient group.

Author: [‘Grootendorst-van Mil N’, ‘Chang CK’, ‘Chandran D’, ‘Schirmbeck F’, ‘van Beveren N’, ‘Shetty H’, ‘Stewart R’, ‘Ahn-Robbins D’, ‘de Haan L’, ‘Hayes RD’]

Journal: Acta Neuropsychiatr

Citation: Grootendorst-van Mil N, et al. Obsessive-compulsive symptoms relating to psychosocial functioning for people with schizophrenia, schizoaffective disorder, or bipolar disorder. Obsessive-compulsive symptoms relating to psychosocial functioning for people with schizophrenia, schizoaffective disorder, or bipolar disorder. 2024; (unknown volume):1-9. doi: 10.1017/neu.2024.42

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