Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024-2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms.

Abstract

The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines produced their first edition in 1999, with subsequent revisions in 2008, 2010, 2016 and 2019. A new iteration of ARIA-ARIA 2024-2025-in collaboration with EAACI is currently being developed, focusing on the management of allergic rhinitis. ARIA 2024-2025 follows the GRADE framework and is endorsed by the European Academy of Allergy and Clinical Immunology (EAACI). A set of approaches has been used to develop guideline questions, including surveying key opinion leaders and using artificial intelligence (AI)-based tools to analyse web searches on allergic rhinitis and to generate questions. Each prioritised guideline question is assessed through an Evidence-to-Decision (EtD) framework. EtDs support the systematic and transparent formulation of recommendations, comprising 12 criteria for which the best available evidence should be sought. In the context of ARIA-EAACI 2024-2025, such evidence is derived not only from randomised controlled trials but also-among others-from patient-generated data sources that better reflect the affected individuals’ perspectives. Moreover, ARIA-EAACI 2024-2025 incorporates evidence on planetary health. Developed guideline recommendations will support the creation of digitalised decision algorithms and care pathways. This paper describes the methodology used to develop the person-centred, digitally enabled and AI-assisted ARIA-EAACI 2024-2025. Among others, it describes (i) the development and prioritisation of guideline questions, (ii) sources of evidence for EtDs and (iii) the development of digitalised decision algorithms and care pathways.

Author: [‘Bousquet J’, ‘Sousa-Pinto B’, ‘Vieira RJ’, ‘Schünemann HJ’, ‘Zuberbier T’, ‘Bognanni A’, ‘Togias A’, ‘Samolinski B’, ‘Valiulis A’, ‘Williams S’, ‘Bedbrook A’, ‘Czarlewski W’, ‘Torres MJ’, ‘Shamji MH’, ‘Morais-Almeida M’, ‘Canonica GW’, ‘Vecillas LL’, ‘Dykewicz MS’, ‘Jacomelli C’, ‘Klimek L’, ‘Leemann L’, ‘Lourenço O’, ‘Palamarchuk Y’, ‘Papadopoulos NG’, ‘Pereira AM’, ‘Savouré M’, ‘Toppila-Salmi SK’, ‘Ventura MT’, ‘Yepes-Nuñez JJ’, ‘Cruz AA’, ‘Ciprandi G’, ‘Gemicioglu B’, ‘Giovannini M’, ‘Gradauskiene B’, ‘Jartti T’, ‘Jeseňák M’, ‘Kuna P’, ‘Kvedariene V’, ‘Larenas-Linnemann DE’, ‘Latiff AHA’, ‘Mohammad Y’, ‘Ohta K’, ‘Mahesh PA’, ‘Pali-Schöll I’, ‘Pfaar O’, ‘Regateiro FS’, ‘Roche N’, ‘Sofiev M’, ‘Taborda-Barata L’, ‘Ulrik CS’, ‘Rostan MV’, ‘Viegi G’, ‘Zhang L’, ‘Antó JM’, ‘Haahtela T’, ‘Cherrez-Ojeda I’, ‘Ivancevich JC’, ‘Khaltaev N’, ‘Yorgancioglu A’, ‘Abdullah B’, ‘Al-Ahmad M’, ‘Al-Nesf MA’, ‘Amaral R’, ‘Asllani J’, ‘Bergmann KC’, ‘Bernstein JA’, ‘Blaiss MS’, ‘Braido F’, ‘Camargos P’, ‘Carreiro-Martins P’, ‘Casale T’, ‘Cecchi L’, ‘Fiocchi AG’, ‘Giuliano AFM’, ‘Christoff G’, ‘Cirule I’, ‘Correia-de-Sousa J’, ‘Costa EM’, ‘Del Giacco S’, ‘Devillier P’, ‘Dokic D’, ‘Hossny E’, ‘Iinuma T’, ‘Irani C’, ‘Ispayeva Z’, ‘Julge K’, ‘Kaidashev I’, ‘Bennoor KS’, ‘Kraxner H’, ‘Kull I’, ‘Kulus M’, ‘Kupczyk M’, ‘Kurchenko A’, ‘La Grutta S’, ‘Miculinic N’, ‘Tuyet LLT’, ‘Makris M’, ‘Milenkovic B’, ‘Lee SM’, ‘Montefort S’, ‘Moreira A’, ‘Mullol J’, ‘Nadif R’, ‘Nakonechna A’, ‘Neffen HE’, ‘Niedoszytko M’, ‘Nyembue D’, “O’Hehir R”, ‘Ogulur I’, ‘Okamoto Y’, ‘Olze H’, ‘Palomares O’, ‘Panzner P’, ‘Patella V’, ‘Pawankar R’, ‘Pitsios C’, ‘Popov TA’, ‘Puggioni F’, ‘Quirce S’, ‘Ramonaité A’, ‘Recto M’, ‘Repka-Ramirez MS’, ‘Roberts G’, ‘Robles-Velasco K’, ‘Rottem M’, ‘Salapatas M’, ‘Sastre J’, ‘Scichilone N’, ‘Sisul JC’, ‘Solé D’, ‘Soto-Martinez ME’, ‘Sova M’, ‘Tantilipikorn P’, ‘Todo-Bom A’, ‘Tsaryk V’, ‘Tsiligianni I’, ‘Urrutia-Pereira M’, ‘Valovirta E’, ‘Van Ganse E’, ‘Vasankari T’, ‘Wallace D’, ‘Wang Y’, ‘Worm M’, ‘Yusuf OM’, ‘Zidarn M’, ‘Gil-Mata S’, ‘Marques-Cruz M’, ‘Mahboub B’, ‘Ansotegui IJ’, ‘Romano A’, ‘Artesani MC’, ‘Barreto B’, ‘Becker S’, ‘Beghe B’, ‘Bouchard J’, ‘Bourgoin-Heck M’, ‘Brussino L’, ‘Buhl R’, ‘Calvo-Gil M’, ‘Dahl VC’, ‘Vizuete JAC’, ‘Charpin D’, ‘Chavannes NH’, ‘Chełmińska M’, ‘Cheng L’, ‘Chkhartishvili E’, ‘Chong-Neto HJ’, ‘Choudhury D’, ‘Chu D’, ‘Cingi C’, ‘Compalati E’, ‘Cvetkovski B’, ‘Da Silva J’, “D’Amato G”, ‘Davies J’, ‘Di Bona D’, ‘Dimou MV’, ‘Teixeira MDC’, ‘Doulaptsi M’, ‘Pérez JMF’, ‘Gawlik R’, ‘Goksel O’, ‘Gómez MR’, ‘Gonzalez Diaz SN’, ‘Gotua M’, ‘Grigoreas C’, ‘Grisle I’, ‘Guzman MA’, ‘Tan RH’, ‘Hyland M’, ‘Ierodiakonou D’, ‘Karavelia A’, ‘Kisiel M’, ‘Kosnik M’, ‘Kritikos V’, ‘Lombardi C’, ‘Martini M’, ‘Meço C’, ‘Mesonjesi E’, ‘Mihaltan F’, ‘Moniuszko M’, ‘Naclerio R’, ‘Neisinger S’, ‘Ordak M’, ‘Paoletti G’, ‘Perdomo-Flores EA’, ‘Pham-Thi N’, ‘Prokopakis E’, ‘Yeverino DR’, ‘Rolla G’, ‘Romantowski J’, ‘Rouadi PW’, ‘Rukhadze M’, ‘Sakurai D’, ‘Salameh L’, ‘Sarquis FS’, ‘Kosak TS’, ‘Soyka M’, ‘Sozinova O’, ‘Specjalski K’, ‘Tomic-Spiric V’, ‘Vachova M’, ‘van Hage M’, ‘Koyuncu IV’, ‘Vichyanond P’, ‘Wagenmann M’, ‘Ko FWS’, ‘Werminghaus P’, ‘Xepapadaki VP’, ‘Xiang YK’, ‘Fonseca JA’]

Journal: Allergy

Citation: Bousquet J, et al. Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024-2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms. Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024-2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms. 2025; (unknown volume):(unknown pages). doi: 10.1111/all.70100