🧑🏼‍💻 Research - June 13, 2025

Impact of a deep-learning image reconstruction algorithm on image quality and detection of solid lung lesions.

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⚡ Quick Summary

This study evaluated the effectiveness of a deep-learning image reconstruction algorithm (Precise Image) compared to an iterative reconstruction algorithm in enhancing image quality and detecting solid lung lesions in chest CT scans. The findings suggest that the Smooth and Smoother levels of the deep-learning algorithm significantly improve image quality and diagnostic confidence.

🔍 Key Details

  • 📊 Participants: 30 patients with solid lung lesions, mean age 70.0 ± 9.0 years
  • ⚙️ Algorithms compared: Iterative reconstruction (Level 4) vs. Deep-learning (Standard/Smooth/Smoother)
  • 📏 Metrics measured: Mean attenuation, standard deviation, contrast-to-noise ratio
  • 🧑‍⚕️ Assessment: Image quality rated by two radiologists using Likert scales

🔑 Key Takeaways

  • 🔍 Image quality improved significantly with the Smooth and Smoother levels compared to the iterative algorithm.
  • 📈 Contrast-to-noise ratio was notably higher with deep-learning algorithms, enhancing lesion visibility.
  • 🩻 Radiologists reported lower image noise with deep-learning algorithms, indicating better diagnostic clarity.
  • 🏆 Overall image quality scores were highest for the Smooth and Smoother levels, suggesting their clinical utility.
  • 💡 Clinical implications indicate that these advanced algorithms can be integrated into routine chest CT acquisitions.

📚 Background

The detection and monitoring of solid lung lesions are critical in the management of various pulmonary conditions. Traditional image reconstruction techniques often struggle with noise and clarity, which can hinder accurate diagnosis. The advent of deep-learning algorithms offers a promising solution, potentially enhancing image quality and diagnostic confidence in radiology.

🗒️ Study

Conducted between December 2021 and February 2022, this retrospective study included all consecutive patients diagnosed with at least one solid lung lesion. The researchers compared images reconstructed using the iterative algorithm (Level 4) with those reconstructed using various levels of the deep-learning algorithm, focusing on key metrics such as attenuation and contrast-to-noise ratio.

📈 Results

The study included 30 patients, with a mean CTDIvol of 6.3 ± 2.1 mGy. While the contrast-to-noise ratio remained similar between the iterative and Standard levels, it significantly increased with the Smooth and Smoother levels (p < 0.05). Radiologists noted a significant reduction in image noise when using the deep-learning algorithms, particularly at the Smoother level, which also received the highest overall image quality scores.

🌍 Impact and Implications

The findings from this study have substantial implications for clinical practice. By adopting the Smooth and Smoother levels of the deep-learning image reconstruction algorithm, radiologists can achieve higher diagnostic confidence and improved image quality in chest CT scans. This advancement could lead to better patient outcomes through more accurate detection and monitoring of lung lesions, ultimately enhancing the quality of care in pulmonary medicine.

🔮 Conclusion

This study highlights the transformative potential of deep-learning algorithms in radiology, particularly for chest CT imaging. The significant improvements in image quality and diagnostic confidence underscore the importance of integrating these technologies into clinical workflows. As we continue to explore the capabilities of AI in healthcare, the future looks promising for enhanced diagnostic tools and patient care.

💬 Your comments

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Impact of a deep-learning image reconstruction algorithm on image quality and detection of solid lung lesions.

Abstract

PURPOSE: To compare the impact of a deep-learning image reconstruction algorithm (Precise Image) with an iterative reconstruction algorithm on image quality and detection of solid lung lesions in chest CT images.
METHODS: All consecutive patients with at least one solid lung lesion diagnosed between December 2021 and February 2022 were retrospectively included. Images were reconstructed using Level 4 of the iterative reconstruction algorithm (i4) and the Standard/Smooth/Smoother levels of the deep-learning image reconstruction algorithm. Mean attenuation and standard deviation were measured by placing regions of interest in fat, muscle, trachea and solid lung lesions. The contrast-to-noise ratio between the lesion and the trachea was computed. Two radiologists assessed image noise and image smoothness, overall image quality and confidence diagnostic level using Likert scales. One radiologist also measured the large axis of the largest lesion. Statistical analyses was performed to compare outcomes obtained with the different algorithms.
RESULTS: Thirty patients with a mean age of 70.0 ± 9.0 years (17 men) were included. The mean CTDIvol was 6.3 ± 2.1 mGy. For all tissues, the contrast-to-noise ratio was similar for i4 and Standard level (p > 0.05) but increased significantly with other deep-learning image reconstruction levels compared to i4 (p < 0.05) and increased significantly from Standard to Smoother. Radiologists rated the image noise with a similar score between i4 and Standard level but decreased significantly between i4 and other deep-learning image reconstruction levels (p < 0.05) and from Standard to Smoother levels (p < 0.01). Overall image quality score were highest for the Smooth and Smoother levels.
CONCLUSION: Smooth and Smoother levels may now be used in clinical practice for chest CT acquisitions in solid lung lesion follow-up.

Author: [‘Greffier J’, ‘Pastor M’, ‘Durand Q’, ‘Sales R’, ‘Serrand C’, ‘Beregi JP’, ‘Dabli D’, ‘Frandon J’]

Journal: Res Diagn Interv Imaging

Citation: Greffier J, et al. Impact of a deep-learning image reconstruction algorithm on image quality and detection of solid lung lesions. Impact of a deep-learning image reconstruction algorithm on image quality and detection of solid lung lesions. 2025; 14:100062. doi: 10.1016/j.redii.2025.100062

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