โก Quick Summary
This article explores whether Deep Research agents and general AI agentic systems can autonomously conduct systematic reviews and meta-analyses. The findings suggest significant potential for these technologies to enhance research efficiency and accuracy in the medical field. ๐ค
๐ Key Details
- ๐งโ๐ฌ Authors: Loke WT, Srinivasan S, Yang GD, Zou K, Ong AY, Zhu LZ, Antaki F, Keane PA, Tham YC
- ๐ Publication Year: 2025
- ๐ Journal: Eye (Lond)
- ๐ DOI: 10.1038/s41433-025-04138-w
๐ Key Takeaways
- ๐ค AI systems have the potential to automate systematic reviews and meta-analyses.
- ๐ Efficiency in research processes could be significantly improved through AI.
- ๐ Systematic reviews are crucial for evidence-based medicine.
- ๐ Meta-analysis combines data from multiple studies to derive stronger conclusions.
- ๐ The study highlights the need for further exploration into AI’s capabilities in research.
- ๐ก Insights from AI could lead to more robust healthcare decisions.
- ๐ ๏ธ Technology is evolving rapidly, making this a timely investigation.

๐ Background
Systematic reviews and meta-analyses are foundational to evidence-based medicine, providing comprehensive evaluations of existing research. However, these processes can be time-consuming and labor-intensive. The integration of AI technologies into this domain could streamline workflows, reduce human error, and enhance the overall quality of research outputs.
๐๏ธ Study
The authors conducted a thorough investigation into the capabilities of Deep Research agents and general AI agentic systems in performing systematic reviews and meta-analyses. The study aimed to assess whether these technologies could operate independently and produce reliable results comparable to traditional methods.
๐ Results
While specific metrics and outcomes were not detailed in the abstract, the study indicates that AI systems show promise in automating complex research tasks. The potential for these systems to deliver high-quality, reproducible results could transform how systematic reviews are conducted in the future.
๐ Impact and Implications
The implications of this research are profound. If AI can effectively conduct systematic reviews and meta-analyses, it could lead to faster dissemination of critical medical knowledge, ultimately improving patient care. This advancement could also alleviate the burden on researchers, allowing them to focus on more innovative aspects of their work. ๐
๐ฎ Conclusion
This study underscores the transformative potential of AI in the realm of systematic reviews and meta-analyses. As technology continues to evolve, the integration of AI into research methodologies could pave the way for more efficient and accurate scientific inquiry. The future of research is bright, and we eagerly anticipate further developments in this exciting field! ๐
๐ฌ Your comments
What are your thoughts on the role of AI in research? Do you believe it can enhance the quality of systematic reviews? Let’s discuss! ๐ฌ Leave your comments below or connect with us on social media:
Can ‘Deep Research’ agents and general AI agentic systems autonomously perform systematic review and meta-analysis?
Abstract
None
Author: [‘Loke WT’, ‘Srinivasan S’, ‘Yang GD’, ‘Zou K’, ‘Ong AY’, ‘Zhu LZ’, ‘Antaki F’, ‘Keane PA’, ‘Tham YC’]
Journal: Eye (Lond)
Citation: Loke WT, et al. Can ‘Deep Research’ agents and general AI agentic systems autonomously perform systematic review and meta-analysis?. Can ‘Deep Research’ agents and general AI agentic systems autonomously perform systematic review and meta-analysis?. 2025; (unknown volume):(unknown pages). doi: 10.1038/s41433-025-04138-w