⚡ Quick Summary
This study presents a hybrid artificial intelligence framework for classifying lung cancer using CT images, significantly improving early detection rates. The model achieved superior performance metrics, including the highest accuracy and precision compared to existing methods.
🔍 Key Details
- 📊 Dataset: Images from the Iraq-Oncology Teaching Hospital/National Center for Cancer Diseases (IQ-OTH/NCCD)
- 🧩 Features used: Traditional methods (GLCM, SIFT) and Deep Learning methods (VGG-16, MobileNet)
- ⚙️ Technology: Hybrid AI model combining feature extraction techniques
- 🏆 Performance: Highest accuracy, precision, recall, F1-score, and specificity achieved with GLCM + SIFT + MobileNet
🔑 Key Takeaways
- 💡 Early detection of lung cancer can significantly improve survival rates.
- 🤖 AI integration in medical imaging enhances the accuracy of lung cancer classification.
- 📈 The hybrid model outperformed traditional methods and other AI approaches.
- 🔍 Feature extraction from both traditional and deep learning methods is crucial for effective classification.
- 🏥 Real-time deployment of the model is feasible, making it suitable for clinical settings.
- 🌍 The study highlights the importance of automated systems in reducing human error in medical diagnostics.

📚 Background
Lung cancer remains one of the most lethal forms of cancer, with a low survival rate compared to other cancers. Early prediction and diagnosis are vital for improving patient outcomes. Traditional imaging techniques, while useful, often fall short in detecting early-stage lung cancer due to the time-consuming nature of manual visualization and the potential for human error. This study addresses these challenges by leveraging artificial intelligence to automate the classification process.
🗒️ Study
The research involved a comprehensive analysis of lung CT images sourced from the IQ-OTH/NCCD dataset. Various pre-processing techniques were applied to the images, followed by feature extraction using both traditional methods like the Gray-Level Co-occurrence Matrix (GLCM) and Scale-Invariant Feature Transform (SIFT), as well as advanced Deep Learning methods such as VGG-16 and MobileNet. The extracted features were then fused and classified using a Fully Connected Layer (FCL).
📈 Results
The study found that the combination of GLCM and SIFT with MobileNet yielded the best results, achieving the highest metrics across the board, including accuracy, precision, recall, F1-score, and specificity. This hybrid model not only surpassed traditional methods but also outperformed other state-of-the-art AI approaches, confirming its reliability for lung cancer prediction from CT images.
🌍 Impact and Implications
The implications of this research are profound. By integrating AI into the diagnostic process, we can enhance the accuracy and speed of lung cancer detection, ultimately leading to better patient outcomes. The ability to deploy this model in real-time clinical settings could revolutionize how lung cancer is diagnosed and treated, paving the way for more effective healthcare solutions.
🔮 Conclusion
This study underscores the transformative potential of artificial intelligence in the realm of medical diagnostics, particularly for lung cancer classification. The hybrid AI framework not only demonstrates superior performance but also offers a promising avenue for real-time application in clinical practice. Continued research and development in this field are essential to further enhance diagnostic accuracy and improve patient care.
💬 Your comments
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An efficient hybrid artificial intelligence framework for lung cancer classification using CT images.
Abstract
Lung cancer is the most dangerous type of cancer, and its affected rate increases gradually. The survival rate of lung cancer is very low compared to other cancers. Early prediction of lung cancer can help increase the survival rate by ensuring sufficient oxygen supply and eliminating carbon dioxide in the human body. Computed Tomography (CT) imaging is widely used by physicians for lung disease identification because it provides detailed cross-sectional views of the lungs and helps in detecting small nodules that may be missed by other imaging techniques. Manual visualization is time-consuming and sometimes leads to classification errors, making it difficult to identify lung cancer at an early stage. This limitation can be addressed through automated lung cancer prediction using Artificial Intelligence (AI). This research proposes a hybrid AI model to classify lung CT images as normal, benign, or malignant. Images from the Iraq-Oncology Teaching Hospital/National Center for Cancer Diseases (IQ-OTH/NCCD) dataset are used. These images undergo various pre-processing techniques, and features are extracted using both traditional methods such as Gray-Level Co-occurrence Matrix (GLCM) and Scale-Invariant Feature Transform (SIFT), and Deep Learning (DL) methods such as Visual Geometry Group (VGG-16) and MobileNet. The extracted features from both approaches are fused and processed through a Fully Connected Layer (FCL) for classification. Six combinations of feature extraction modules are evaluated for lung cancer prediction: GLCM + MobileNet, GLCM + VGG-16, SIFT + MobileNet, SIFT + VGG-16, GLCM + SIFT + MobileNet, and GLCM + SIFT + VGG-16. Among these combinations, the integration of GLCM and SIFT with MobileNet demonstrates superior performance compared to other AI combinations, achieving the highest accuracy, precision, recall, F1-score, and specificity. The proposed methodology is also compared with state-of-the-art methods, and the results indicate that the hybrid AI model surpasses existing approaches. The experimental findings confirm that the proposed model provides reliable results for lung cancer prediction from CT images and is suitable for real-time deployment.
Author: [‘Kamala L’, ‘Mohan KG’]
Journal: Sci Rep
Citation: Kamala L and Mohan KG. An efficient hybrid artificial intelligence framework for lung cancer classification using CT images. An efficient hybrid artificial intelligence framework for lung cancer classification using CT images. 2025; (unknown volume):(unknown pages). doi: 10.1038/s41598-025-31432-0