โก Quick Summary
The EndoCompass project aims to address the significant gap in research funding for endocrine science, particularly in thyroid disorders. By establishing strategic research priorities, this initiative seeks to enhance our understanding and treatment of thyroid-related health challenges.
๐ Key Details
- ๐ Focus Area: Thyroid endocrinology
- ๐งฉ Methodology: Analysis of the EU CORDIS database and expert consultations
- โ๏ธ Key Technologies: Personalized medicine, artificial intelligence
- ๐ Stakeholders: Endocrine societies, patient advocacy groups
๐ Key Takeaways
- ๐ Research priorities include both neoplastic and nonneoplastic thyroid conditions.
- ๐ก Emphasis on understanding disease mechanisms and improving diagnostics.
- ๐ค Innovative approaches such as personalized medicine and AI applications are highlighted.
- ๐ Establishment of pan-European registries to advance research on rare thyroid conditions.
- ๐ Evidence-based roadmap for strategic investment in thyroid research is provided.
- ๐ Alignment of research funding with areas of highest potential impact in endocrine health.
- ๐ฅ Aim to reduce the burden of thyroid disorders on individuals and society.
๐ Background
Despite the critical role of hormones in human health, endocrine science has been underrepresented in European Union research initiatives. This discrepancy highlights a pressing need for increased attention and funding towards understanding and treating endocrine disorders, particularly those affecting the thyroid.
๐๏ธ Study
The EndoCompass project involved a comprehensive analysis of the EU CORDIS database from the Horizon 2020 framework (2014-2020) to identify key research priorities in thyroid endocrinology. Expert consultations were conducted to gather insights from professionals in the field, followed by engagement with broader stakeholders, including society members and patient advocacy groups.
๐ Results
The findings revealed that research priorities for thyroid disorders focus on understanding both neoplastic and nonneoplastic conditions. Key areas of interest include disease mechanisms, improved diagnostics, and the influence of environmental and metabolic factors. Notably, the project emphasizes the importance of personalized medicine and the application of artificial intelligence in advancing thyroid health.
๐ Impact and Implications
The EndoCompass project has the potential to significantly impact thyroid health research by providing a structured framework for strategic investment. By aligning research funding with critical areas, the initiative aims to enhance our understanding of thyroid disease pathophysiology and improve prevention and treatment strategies, ultimately benefiting individuals and society as a whole.
๐ฎ Conclusion
The EndoCompass project represents a vital step towards addressing the research gaps in thyroid endocrinology. By focusing on strategic research priorities and innovative approaches, this initiative holds promise for advancing our understanding and treatment of thyroid disorders. Continued support and investment in this area are essential for improving health outcomes related to endocrine health.
๐ฌ Your comments
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EndoCompass Project: Research Roadmap for Thyroid Endocrinology.
Abstract
BACKGROUND: Endocrine science remains underrepresented in European Union research programs despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritization. At national funding level, endocrine societies report limited or little attention of national research funding toward endocrinology. The EndoCompass project – a joint initiative between the European Society of Endocrinology and the European Society of Paediatric Endocrinology, aimed to identify and promote strategic research priorities in endocrine science to address critical hormone-related health challenges.
METHODS: Research priorities were established through comprehensive analysis of the EU CORDIS database covering the Horizon 2020 framework period (2014-2020). Expert consultation in thyroid endocrinology was conducted to identify key research priorities, followed by broader stakeholder engagement including society members and patient advocacy groups.
RESULTS: For thyroid disorders, research priorities encompass neoplastic and nonneoplastic conditions, focusing on disease mechanisms, improved diagnostics and treatments, and the impact of environmental and metabolic factors. Key areas include personalized medicine approaches, artificial intelligence applications, and the establishment of pan-European registries to advance understanding of rare thyroid conditions.
CONCLUSIONS: The thyroid component of the EndoCompass project provides an evidence-based roadmap for strategic research investment. This framework identifies crucial investigation areas into thyroid disease pathophysiology, prevention, and treatment strategies, ultimately aimed at reducing the burden of thyroid disorders on individuals and society. The findings support the broader EndoCompass objective of aligning research funding with areas of highest potential impact in endocrine health.
Author: [‘Piekielko-Witkowska A’, ‘Elisei R’, ‘Lรฉger J’, ‘Bendlova B’, ‘Bulanovรก Pekova B’, ‘Caron P’, ‘Durante C’, ‘Fassnacht M’, ‘Feldt-Rasmussen U’, ‘Filipsson Nystrรถm H’, ‘Jansen H’, ‘Kรถhrle J’, ‘Kus A’, ‘Ludgate M’, ‘Mertens J’, ‘Oczko-Wojciechowska M’, ‘Peters C’, ‘Schoenmakers N’, ‘Stoupa A’, ‘van Santen H’, ‘Trimboli P’, ‘van Trotsenburg P’, ‘Visser WE’]
Journal: Horm Res Paediatr
Citation: Piekielko-Witkowska A, et al. EndoCompass Project: Research Roadmap for Thyroid Endocrinology. EndoCompass Project: Research Roadmap for Thyroid Endocrinology. 2025; (unknown volume):1-14. doi: 10.1159/000549075