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🧑🏼‍💻 Research - September 30, 2024

Artificial intelligence in reproductive endocrinology: an in-depth longitudinal analysis of ChatGPTv4’s month-by-month interpretation and adherence to clinical guidelines for diminished ovarian reserve.

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⚡ Quick Summary

A recent study evaluated the performance of ChatGPTv4 in adhering to clinical guidelines for Diminished Ovarian Reserve (DOR) over two months. The findings revealed that ChatGPTv4 achieved near-perfect accuracy, demonstrating its potential as a reliable tool in reproductive endocrinology. 🤖

🔍 Key Details

  • 📊 Study Design: Longitudinal analysis over two months
  • 🧩 Questionnaire: 176 open-ended, 166 multiple-choice, and 153 true/false questions
  • ⚙️ AI Model: ChatGPTv4
  • 🏆 Performance Metrics: Near-perfect accuracy across all question types

🔑 Key Takeaways

  • 📈 Accuracy: 100% accuracy in true/false questions.
  • 📊 Improvement: Multiple-choice accuracy increased from 98.2% to 100% over two months.
  • 📚 Open-ended responses: Accuracy improved significantly from 5.38 to 5.74 (max: 6.0).
  • 💡 Completeness: Scores rose from 2.57 to 2.85 (max: 3.0).
  • 🔍 Statistical Significance: Improvements were significant (p < 0.001).
  • 🔗 Correlation: Positive correlations between initial and follow-up scores (r = 0.597 for accuracy, r = 0.381 for completeness).
  • 🌐 Limitations: Study conducted in a controlled, simulated environment.
  • 🌟 Conclusion: ChatGPTv4 shows promise as a tool for enhancing clinical decision-making in reproductive endocrinology.

📚 Background

Diminished Ovarian Reserve (DOR) is a critical concern in reproductive endocrinology, affecting women’s fertility and treatment options. The integration of artificial intelligence in this field could provide valuable insights and support for clinicians, enhancing the accuracy of medical advice and adherence to established guidelines.

🗒️ Study

This study was designed to quantitatively assess the performance of ChatGPTv4 in interpreting DOR-related questionnaires based on standardized clinical guidelines. The structured questionnaire was administered to the AI model, allowing researchers to evaluate its responses for accuracy and completeness over a two-month period.

📈 Results

The results were impressive, with ChatGPTv4 achieving 100% accuracy in true/false questions and a notable improvement in multiple-choice questions. Open-ended responses also showed significant enhancements, indicating that the AI model not only maintained high performance but also improved over time, with statistical significance in the observed changes.

🌍 Impact and Implications

The findings of this study suggest that ChatGPTv4 could serve as a valuable resource in reproductive endocrinology, aiding clinicians in decision-making and potentially improving patient outcomes. As AI continues to evolve, its integration into clinical practice may lead to more consistent and reliable medical advice, ultimately benefiting patients facing challenges related to DOR.

🔮 Conclusion

This study highlights the remarkable potential of artificial intelligence in reproductive endocrinology, particularly in managing DOR-related queries. The consistent and improving performance of ChatGPTv4 underscores its capability to support clinical decision-making and enhance adherence to guidelines. Continued research in this area is essential to fully realize the benefits of AI in healthcare. 🌟

💬 Your comments

What are your thoughts on the use of AI in reproductive health? We would love to hear your insights! 💬 Share your comments below or connect with us on social media:

Artificial intelligence in reproductive endocrinology: an in-depth longitudinal analysis of ChatGPTv4’s month-by-month interpretation and adherence to clinical guidelines for diminished ovarian reserve.

Abstract

OBJECTIVE: To quantitatively assess the performance of ChatGPTv4, an Artificial Intelligence Language Model, in adhering to clinical guidelines for Diminished Ovarian Reserve (DOR) over two months, evaluating the model’s consistency in providing guideline-based responses.
DESIGN: A longitudinal study design was employed to evaluate ChatGPTv4’s response accuracy and completeness using a structured questionnaire at baseline and at a two-month follow-up.
SETTING: ChatGPTv4 was tasked with interpreting DOR questionnaires based on standardized clinical guidelines.
PARTICIPANTS: The study did not involve human participants; the questionnaire was exclusively administered to the ChatGPT model to generate responses about DOR.
METHODS: A guideline-based questionnaire with 176 open-ended, 166 multiple-choice, and 153 true/false questions were deployed to rigorously assess ChatGPTv4’s ability to provide accurate medical advice aligned with current DOR clinical guidelines. AI-generated responses were rated on a 6-point Likert scale for accuracy and a 3-point scale for completeness. The two-phase design assessed the stability and consistency of AI-generated answers over two months.
RESULTS: ChatGPTv4 achieved near-perfect scores across all question types, with true/false questions consistently answered with 100% accuracy. In multiple-choice queries, accuracy improved from 98.2 to 100% at the two-month follow-up. Open-ended question responses exhibited significant positive enhancements, with accuracy scores increasing from an average of 5.38 ± 0.71 to 5.74 ± 0.51 (max: 6.0) and completeness scores from 2.57 ± 0.52 to 2.85 ± 0.36 (max: 3.0). It underscored the improvements as significant (p < 0.001), with positive correlations between initial and follow-up accuracy (r = 0.597) and completeness (r = 0.381) scores. LIMITATIONS: The study was limited by the reliance on a controlled, albeit simulated, setting that may not perfectly mirror real-world clinical interactions. CONCLUSION: ChatGPTv4 demonstrated exceptional and improving accuracy and completeness in handling DOR-related guideline queries over the studied period. These findings highlight ChatGPTv4's potential as a reliable, adaptable AI tool in reproductive endocrinology, capable of augmenting clinical decision-making and guideline development.

Author: [‘Gurbuz T’, ‘Gokmen O’, ‘Devranoglu B’, ‘Yurci A’, ‘Madenli AA’]

Journal: Endocrine

Citation: Gurbuz T, et al. Artificial intelligence in reproductive endocrinology: an in-depth longitudinal analysis of ChatGPTv4’s month-by-month interpretation and adherence to clinical guidelines for diminished ovarian reserve. Artificial intelligence in reproductive endocrinology: an in-depth longitudinal analysis of ChatGPTv4’s month-by-month interpretation and adherence to clinical guidelines for diminished ovarian reserve. 2024; (unknown volume):(unknown pages). doi: 10.1007/s12020-024-04031-8

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